A Strategy to Design Protein-based Antagonists Against Type I Cytokine Receptors

Authors: Timo Ullrich, Olga Klimenkova, Christoph Pollmann, Asma Lasram, Valeriia Hatskovska, Kateryna Maksymenko, Matej Milijaš-Jotić, Lukas Schenk, Claudia Lengerke, Marcus D. Hartmann, Jacob Piehler, Julia Skokowa, Mohammad ElGamacy

Published in: PloS Biology (Accepted)

Year: 2024

A New Severe Congenital Neutropenia Syndrome Associated with Autosomal Recessive COPZ1 Mutations

Authors:Natalia Borbaran Bravo, Ekaterina Deordieva, Larissa Doll, Mohammad ElGamacy, Benjamin Dannenmann, Joana Azevedo, Alberto Iannuzzo, Selket Delafontaine, Moritz Lehnerz, Marius Kolodziej, Birte Hernandez-Alvarez, Anna-Sophia Hellmuth, Betül Findik, Viktoria Zakharova, Sandro Bräuning, Sergey Kandabarau, Claudia Lengerke, Robert Feil, Isabelle Meytz, Jérome Delon, Markus Templin, Marc Sturm, Olaf Rieß, Cornelia Zeidler, Karl Welte, Anna Shcherbina, Maksim Klimiankou, Julia Skokowa

Published in:Blood (Accepted)

Year: 2024

The Damietta Server: A Comprehensive Protein Design Toolkit

Authors:Iwan Grin, Kateryna Maksymenko, Tobias Wörtwein, Mohammad ElGamacy

Published in:Nucleic Acids Research

Year: 2024

The design of functional proteins using tensorized energy calculations

Authors:Kateryna Maksymenko, Andreas Maurer, Narges Aghaallaei, Caroline Barry, Natalia Borbarán-Bravo, Timo Ullrich, Tjeerd Dijkstra, Birte Hernandez Alvarez, Patrick Müller, Andrei Lupas, Julia Skokowa, Mohammad ElGamacy

Published in:Cell Reports Methods

Year: 2023

A topological refactoring design strategy yields highly stable granulopoietic proteins

Authors:Julia Skokowa, Birte Hernandez Alvarez, Murray Coles, Malte Ritter, Masoud Nasri, Jérémy Haaf, Narges Aghaallaei, Yun Xu, Perihan Mir, Ann-Christin Krahl, Katherine W. Rogers, Kateryna Maksymenko, Baubak Bajoghli, Karl Welte, Andrei Lupas, Patrick Müller, Mohammad ElGamacy

Published in:Nature Communications

Year: 2022

Design of Novel Granulopoietic Proteins by Topological Rescaffolding

Authors:Birte Hernandez Alvarez, Julia Skokowa, Murray Coles, Perihan Mir, Masoud Nasri, Kateryna Maksymenko, Laura Weidmann, Katherine W. Rogers, Karl Welte, Andrei Lupas, Patrick Müller, Mohammad ElGamacy

Published in:PLoS Biology

Year: 2020